Escape from the normal limitation on growth of a finite number of division cycles (the Hayflick limit), by variants in animal cell cultures, and cells in some tumours. Immortalization in culture may be spontaneous, as happens particularly readily in mouse cells, or induced by mutagens or by transfection of certain oncogenes.

Dictionary of molecular biology. 2004.

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  • Immortalization — Im*mor tal*i*za tion, n. The act of immortalizing, or state of being immortalized. [1913 Webster] …   The Collaborative International Dictionary of English

  • immortalization — immortalization. См. иммортализация. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • immortalization — index dedication, preservation, remembrance (commemoration) Burton s Legal Thesaurus. William C. Burton. 2006 …   Law dictionary

  • immortalization — (n.) c.1600, noun of action or state from IMMORTALIZE (Cf. immortalize) …   Etymology dictionary

  • immortalization — (Amer.) n. act of immortalizing, being immortalized (also immortalisation) …   English contemporary dictionary

  • immortalization — noun see immortalize …   New Collegiate Dictionary

  • immortalization — See immortalize. * * * …   Universalium

  • immortalization — noun The act of immortalizing, or state of being immortalized …   Wiktionary

  • immortalization — Conferring on normal cells cultured in vitro the property of an infinite lifespan, as from spontaneous mutation, by exposure to chemical carcinogens, or by viral infection. I. of primary cells in culture is the first of several steps in the… …   Medical dictionary

  • immortalization — im·mor·tal·iza·tion …   English syllables

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